该【肿瘤转移英文版 】是由【licaia】上传分享,文档一共【26】页,该文档可以免费在线阅读,需要了解更多关于【肿瘤转移英文版 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。Englishversionoftumormetastasis目录contentsOverviewofTumorMetastasisThemechanismoftubermetastasisDiagnosisandmonitoringoftubermetastasisTreatmentoftubermetastasisPreventionandcontroloftubermetastasisOverviewofTumorMetastasisCATALOGUE01anismsorissuesthroughthebloodstreamorlymphaticsystemItisthemaincauseofcancerrelateddeath,asmeteorologicaltutorsareoftendifficulttotreateffectivelyicmutationsandinteractionswiththetumormicroenvironmentDefinitionanismsorissuesTumorcellsextravasatethroughtheendometriallayerandcolonizeinthenewenvironmenttoformsecondarytutorsTumorcellsdetachfromtheprimarytuberandenterthebloodstreamorlymphaticsystemTheprocessoftubermetathesisClassificationoftubermetathesisLinearmetastasisCancercellsspreadthroughthelinearsystemtolinearnodesandotherissuesHematogenousmetastasisanismssuchasthelungs,liver,bones,andbrainIntroductorymetastasisCancercellsspreadwithinthelungstodifferentlobesorsegmentsRetrogrademetastasisCancercellsspreadfromasmallsitebacktothelymphnodesneartheprimarytutorThemechanismoftubermetastasisCATALOGUE02SelfrenewTumorcellshavetheabilitytoreplicateandformnewTumorcellsTumorcellscaninvadesurroundingissuesandmigratetootherpartsofthebodyTumorcellscanevolvetheprogrammedcelldeathprocess,allowingthemtosurviveandcontinuegrowinganizationsorissuesInvasiveResistancetoApoptosisMetastaticpotentialThebiologicalcharacteristicsoftumorcellsInvasivebehavioroftutorcellsTumorcellscanundergochangesintheirmorphologyandbehavior,enablingthemtoadapttodifferentmicroenvironmentsduringmetastasisCellularplasticityTumorcellsunderaprocesscalledEMT,emoremobileEpithelialmesenchymaltransition(EMT)TumorcellssecretproteolyticenzymesthatcandegradetheECM,allowingthemtopassthroughtheissuebarriersDegradationoftheextracellarmatrix(ECM)ChemotaxisTumorcellscansensechemotacticsignalsandmigratetowardsthem,oftenfollowinggradientsofchemoattractantsHaptotaxisandtaxesTumorcellscanadapttospecificligandsontheendometriumandmigratealongtheirligands,aprocessknownasHaptotaxis,ortheycanmigrateinresponsetofluidshearstress,knownastaxesIntravasationandextravasationTumorcellscanenterbloodvessels(intravasation)andexitfromthem(extravasation),anizationsorissuesMigrationanddiffusionoftuitioncells
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