中国医科大学病理学英文课件7.ppt

该【中国医科大学病理学英文课件7 】是由【落意心】上传分享，文档一共【69】页，该文档可以免费在线阅读，需要了解更多关于【中国医科大学病理学英文课件7 】的内容，可以使用淘豆网的站内搜索功能，选择自己适合的文档，以下文字是截取该文章内的部分文字，如需要获得完整电子版，请下载此文档到您的设备，方便您编辑和打印。中国医科大学病理学英文课件7plementSystem:(1)ponentproteintogetherwiththeircleavageproducts:presentasinactiveforms(C1~C9)(2)Functions:Increasevasopermeability(C3a,C5a)Causevasodilation(C3a,C5a)Chemotaxist(C5a)Opsonization(C3b)C3a,5aincreasevascularpermeabilitycausevasodilationbyreleasinghistaminefrommastcellsC5aApowerfulchemotacticagentforneutrophilsbasophils,eosinophils,monocytesActivatesthelipoxygenasepathwayofAAmetabolisminmonocytes,neutrophils→releaseofmediators3)Clottingandfibrinolyticsystem①Activatedclottingsystem:i)Thrombinandfibrinopeptide:ThrombinpromotesleukocyteadhesionfibroblastproliferationFibrinopeptideincreasedVpermeabilitychemotacticactivityforleukocytesii)FactorXaincreasedVpermeabilityleukocyteexudation②ActivatedfibrinolyticsystemC3C3aincreasevpermeabilityvasodilationFibrintofibrinproducts:,bradykinin,PGI2,PGE2,NOPermeabilityhistamine,bradykinin,LTB4,C3a,C5a,PAFChemotaxisLTB4,C5a,cytokins,cationicproteinFeverIL-1,IL-2,TNFa,PGE2PainPGE2,bradykininTissuedamageoxyradical,Lysosomalenzymes,:,virusinfectionintoxication:urea,(1)Mucosafibrinousinflammation:①Sitesupperrespiratorytractgastrointestinaltract②Feature:pseudomembranousinflammationFibrin+necrotictissue+neutrophils→gray-white,membrane-shaped③Common:bacillarydysentery,diphtheria