Obstetrics and Gynecology Hospital of Fudan University Abortion Concept A pregnancy loss before 28 weeks of gestation while fetal weight under 1000 grams Early Abortion:pregnancy loss before 12 gestational weeks Late Abortion: pregnancy loss during 12~28 gestational weeks Spontaneous Abortion Artificial Abortion ic defect Maternal factors: systematic disease; an anomalies; endocrine anomalies; irritation; bad habit Immune anomalies Environmental factors Etiology Pathology Before 8 weeks: chorionic villi immature Fetal death→basal decidual bleeding →uterine contraction→expulsion of all the products of conception, light bleeding During 8~12 weeks:with firm attachment to the basal decidua Partial expulsion of the products of conception→ non-ideal uterine contraction, severe bleeding After 12 weeks: placenta fully formed. Uterine contraction→ expulsion of all the products of conception,light bleeding Symptoms Amenorrhea, vaginal bleeding , and abdominal pain Early abortion:vaginal bleeding preceding abdominal pain Late abortion:abdominal pain preceding vaginal bleeding Types of Abortion Threatened Abortion Inevitable Abortion plete plete Abortion Missed Abortion Habitual Abortion Septic Abortion Clinical Presentations Threatened Abortion light vaginal bleeding with mild abdominal pain cervical os closed, fetal membranes unbroken treatment might work , continue pregnancy Inevitable Abortion bleeding heavier, abdominal pain more severe, or fluid passed cervical os open,pregnancy tissue visible abortion is inevitable plete Abortion heavy vaginal bleeding pregnancy tissue protruding from the cervical os uterus small for the presumed gestational week Complete Abortion vaginal bleeding decreasing, abdominal pain alleviating cervical os closed uterus normal for the presumed gestational week Different Stages of Abortion threatened abortion continue pregnancy inevitable abortion plete abortion