化疗方案.doc

化疗方案46315阿霉素(ADM)表阿霉素(EPI)多西他赛注射液(TXT)***脲嘧啶(5-Fu)环磷酰***(CTX)甲氨喋呤(MTX)吡喃阿霉素(THP)顺铂(DDP)紫杉醇注射液(PTX)重酒石酸长春瑞滨(NVB)TA方案:TXT-多西他赛;ADM-EFTPAF方案:ADM-阿霉素;5-FU-5-***脲嘧啶AC方案:ADM-阿霉素;CTX-环磷酸***CMF方案:CTX-环磷酰***;MTX-氨甲喋呤;5-Fu5-***脲嘧啶。含蒽环类的CAF(CEF)方案在改善乳腺癌病人生存率方面疗效略好于CMF方案,CAF(CEF)方案目前已取代CMF方案而成为乳腺癌化疗的标准化疗方案;紫杉醇及多西紫杉醇联合阿霉素、环磷酰***(TAC)方案在临床上应用较好。目前来说含紫杉醇类方案效果较好。因此在无禁忌证的前提下,尽可能地进行联合化疗已成为乳腺癌化疗的共识。化疗方案药物组成剂量(mg/m2)途径与时间周期间隔周期数CAF环磷酰***阿霉素5-***尿嘧啶50050500Iv,dlIv,dlIv,dl3周3周3周666FAC5-***尿嘧啶阿霉素环磷酰***60060600Iv,dl、8Iv,dlIv,dl4周4周4周444AC阿霉素环磷酰***阿霉素6060060~90Iv,dlIv,dlIv,dl3周3周3周44前4TAC泰索帝阿霉素环磷酰***7550500Iv,dlIv,dlIv,dl3周3周3周666CAF环磷酰***阿霉素5-***尿嘧啶50050500Iv,dlIv,dlIv,dl3周3周3周666CEF100环磷酰***表柔比星5-***尿嘧啶500100500Iv,dlIv,dlIv,dl3周3周3周666CEF大剂量法环磷酰***表柔比星5-***尿嘧啶7560500Po,d1~14Iv,dl、8Iv,dl、84周4周4周666FEC1005-***尿嘧啶表柔比星环磷酰***500100500Iv,dl、8Iv,dlIv,dl4周4周4周666A—CMF阿霉素环磷酰***甲氨蝶呤5-***尿嘧啶7560040600Iv,dlIv,dlIv,dlIv,dl3周3周3周3周前4后8后8后8AC—T环磷酰***紫杉醇600175Iv,dlIv,dl3周3周前4后4他莫昔芬/表柔比星表柔比星他莫昔芬5020mg/dIv,dl、8口服,持续4年4周6CMF(静脉3周法)环磷酰***甲氨蝶呤5-***尿嘧啶60040600Iv,dlIv,dlIv,dl3周3周3周121212CMF(经典法)环磷酰***甲氨蝶呤5-***尿嘧啶10040600Po,d1~14Iv,dl、8Iv,dl、84周4周4周666CMF(静脉4周法)环磷酰***甲氨蝶呤5-***尿嘧啶60040600Iv,dl、8Iv,dlIv,dl、84周4周4周121212CMF(静脉改良法)环磷酰***甲氨蝶呤5-***尿嘧啶50040600I