Cervical cancer.ppt

CervicaltumorCervicalintraepithelialneoplasia(CIN)IntroductionAgroupofprecancerouslesioncloselyassociatedwiththecervicalcancer,(1).atypicalsquamouscells,ABC.(2).low-gradesquamousintraepitheliallesion,LSIL.(3).high-gradesquamousintraepitheliallesion,,,(humanpapillomaviruses)infectionEpidemiologicriskfactorsforCIN:1,multiplesexualpartners2,high-risksexualpartner3,earlyonsetofsexualactivity(<16)4,ahistoryofSTDs(especially,HPVinfection)5,cigarettesmoking6,immunodeficiency7,long-temoralcontraceptivepilluseCervicalHistologicalSpecialty(i).primalsquamo-columnarjunction(ii).physiologicsquamo-columnarjunction(iii).transformationzone(iv).squamousmetaplasia(v).squamousepithelizationPathologyCervicalintraepithelialneoplasia(CIN)degreeI:ie,milddysplasia,upylower1/3layerdegreeII:ie,moderatedysplasia,upythelower2/3layerdegreeIII:ie,severedysplasiaandcarcinomainsitu,upywholelayerClinicalfindingsUsuallynosymptomsorsignsEarlydetectionisextremelyimportantDiagnosisRepeatedcervicalctyology--TCTColposcopicexaminationBiopsy—themostreliablemethodtomakediagnosis