ayurvedic formulation of liv-pro-08 reduces nonalcoholic fatty liver disease in rats fed with high-fat diet英文.pdf

J Acupunct Meridian Stud 2011;4(4):236e241
- RESEARCH ARTICLE -
Ayurvedic Formulation of Liv-Pro-08 Reduces
Nonalcoholic Fatty Liver Disease in Rats Fed
with High-fat Diet
M. Suriyavathana Vedanarayanan y,*, Nandhini Krishnan y
Department of Biochemistry, Periyar University, Salem-11, Tamilnadu, India
Available online Oct 18, 2011
Received: Mar 11, 2011 Abstract
Revised: May 6, 2011 Nonalcoholic fatty liver disease (NAFLD) has emerged as a serious obesity-related
Accepted: Jun 21, 2011 disorder, and it will continue to be a major liver health issue worldwide in the coming
decades. We aimed to determine the effect of Liv-Pro-08 (Nigella sativa, Entada
KEYWORDS pursaetha, and Ficus glomerata) an oral ayurvedic formulation on rats fed with high-
lipid profiles; fat diet. Rats were given a high-fat diet for a period of 7 days. After this period, Liv-
LIV-Pro-08; Pro-08 (250, 500, and 750 mg/ weight was given orally for 7 days. We examined
liver marker enzymes; the effect of the high-fat diet on various parameters related to obesity and insulin resis-
NAFLD; tance. In the experimental rats who received the extract of Liv-Pro-08,