肿瘤免疫学-2013版七年制课件.ppt

Tumor Immunology Yi Zhao 赵义 Dept. of Rheumatology & Immunology, Xuanwu Hospital Questions : ?你所认识的人中没有没因为肿瘤离你而去的? ?你对肿瘤的态度是什么?恨 or绝望无耐 or无所谓……? ?你认为人类最终能战胜肿瘤吗? ?你猜测治疗肿瘤最有希望的方法将会是什么? Hepatocellular carcinoma Cervical cancer Lung cancer Nasopharyngeal carcinoma Lymphoma Pancreatic carcinoma Cancer is the second leading cause of death in USA 引自: 2008 年中国卫生事业统计公报①知可以战与不可以战者胜, ②识众寡之用者胜, ③上下同欲者胜, ④以虞待不虞者胜, ⑤将能而君不御者胜。此五者,知胜之道也。《孙子·谋攻》了解自身了解肿瘤战胜肿瘤 Tumor immunology 肿瘤免疫学( tumor Immunology ):是研究肿瘤的抗原性、机体的免疫功能与肿瘤发生、发展的相互关系,机体对肿瘤的免疫应答及其抗肿瘤免疫的机制、肿瘤的免疫诊断和免疫防治的科学。 Evidence for Tumor Immunity ? The high frequency of cancers in immunosuppressed patients ? Extremes of age ? Primary and secondary immunodeficiency ? Immunosuppressive drugs ? Tumors that are infiltrated by T cells have an improved prognosis ? Spontaneous regression occurs ? Melanoma, breast, lung cancers