脓毒血症文献报道新进展文献汇报课件.ppt

文献汇报一、 High versus Low Blood-Pressure Target in Patients with Septic Shock -----March 18, 2014, at Background ? The Surviving Sepsis Campaign 推荐目标平均动脉压≥ 65 mm Hg during initial resuscitation of patients with septic shock ?比较: 该血压目标与更高的血压目标 Methods ? ~ , 29 个中心, 776 例?分组: MAP: 80 to 85 mm Hg ( high-target )---388 例 65 to 70 mm Hg ( low-target )----388 例?观察 28 天死亡率 Results 1、 At 28 days, 组间无显著区别 Death 142 of 388 high-target group ( % ) 132 of 388 in the low-target group ( % ) (P = ). Results 2、 90 days 也无显著区别, 170 deaths ( % ) VS 164 deaths ( % ) P = 3、严重并发症发生率组间无显著区别 74 events [ % ] VS 69 events [ % ] P = Results ?4、 However, 新诊断的房颤发病率,高压组> 低压组 Results ?5、慢性高血压人群中(占研究人群 40%) ,需要进行肾脏替代治疗的患者,高压组比低压组更少, 但没有导致死亡率的差别。 Results