Effects of acupuncture on serotonin and norepinephrine in hippocampus of depressed model rats 【Abstract】Objective To observe hoechanism of depression model Using Open-Field method to randomly select 40 adult SD male rats into normal control, model group, drug treatment and acupuncture treatment group, 10 rats per group. Separation, long term unpredictability, medium stimulation techniques odify rats behavior. The n using Open-Field method to reflect changes in depressed model rats behavior betonoamine neurotransmitters and thEir metabolites in hippocampus of rat brain ined by HPLC-ECD. Results pared al control, acupuncture treatment group’s behavior ent. On the 21th day after treatment, acupuncture treatment group’s behavior ent group, and ore different odel group(P<). pared al group on the 21th day of treatment, the concentration of serotonin and norep