黄疸级一系老麻醉救援心理陶小红.ppt

该【黄疸级一系老麻醉救援心理陶小红 】是由【小可爱】上传分享，文档一共【37】页，该文档可以免费在线阅读，需要了解更多关于【黄疸级一系老麻醉救援心理陶小红 】的内容，可以使用淘豆网的站内搜索功能，选择自己适合的文档，以下文字是截取该文章内的部分文字，如需要获得完整电子版，请下载此文档到您的设备，方便您编辑和打印。黄疸级一系老麻醉救援心理陶小红Jaundiceoricterus:Whatisjaundice?ClinicallyitistheyellowdiscolorationoftheSclera(巩膜)SkinMucousmembraneduetodepositionofbilepigment(bilirubin胆红素)Serumtotalbilirubin(-)Conjugatedbilirubin:0-,Unconjugatedbilirubin:-.+3NADPHNADP+(openstheporphyrinring)BILIRUBINNADPHNADP+BILIRUBINdiglucuronideBILETheFateofBilirubin…Alb=albumin B=bilirubin GST=glutathione-S-transferaseUDPGA=uridinediphosphoglucuronicacid; CB=conjugatedbilirubinUGT1A1=UDP-glucuronosyltransferase1A1MRP2=Multi-drugResistanceProtein2AdaptedfromHarrison’s15thEd.“PrinciplesofInternalMedicine”,+GSTCBPlasmaellBileAlbBAlb?:GSTBsERB+UDPGAUGT1A1BilirubinExcretionIntestinesLiverBCBCBBUrobilinogenB-glucoronidasebacteriabacteriaBileirculationKidneyUrobilinoxUrobilinogenUrobilinStercobilinStercobilingogenfecesUrineoxLiverAlbuninHemeFerrohemetransferaseBilirubinConjugatedbilirubinKidneyUrobilinStercobilinogenUrobilinogenIntestinesAlbuminBilirubinreductaseHemeGlobinHemoglobinoxidaseBiliverdinMarrowInfantilityErythrocyteFerrohemeEnzyme15%~20%Bilirubin|AlbuminErythrocyte80%~85%UDPUDPGABilirubinglucuronolactoneurobilinogenirculationY/ (溶血性黄疸) HepatocellularJaundice(肝细胞性黄疸)CholestaticJaundice(胆汁淤积性黄疸)Congenitaljaundice (先天性黄疸)(thalassemia(海洋性贫血),hereditaryspherocytosis(遗传性球形红细胞增多症)).(autoimmunityhemolyticanemia,hemolyticdiseaseofnewborn,posttransfusionhemolytic,Favism(蚕豆病).MechanismAlargenumberoferythrocytedestroyedrapidlyAnemia,:lighttodeepyellow,mildskinitch(痒)Tired,lossofappetitehemorrhagictendency,