改良老年疾病累计评分表在老年食管癌患者中应用.docx

group, the ages ranged form 65 to 84 (mean age=72);45 patients were enrolled in the control group, the ages ranged form 35 to 64 (mean age=56).41 patients orbidities in the elderly group (41/57), while 21 in the control group (21/45).There was a significant difference of the prevalence orbidity between the two groups (P<).In two groups orbidities, a significant difference was found in hypertension( P=0. 002) and chronic respiratory diseases( P=0. 023) but not t he ot her s(P>). In the elderly group, the orbidities were hypertension (24 cases, %), and chronic respiratory diseases (16 cases, %), and in the control group, the orbidities were digestive diseases such as chronic gastritis (11 cases, %), cholecystitis and gallbladder stones (n=7cases, %). MCIRS-G score (z = , P = ) and the number of systems affected by plications of the elderly group were higher than the control group. Based
on MCIRS-G score and age, 90 patients with chemotherapy were divided into 14,15,
16,17and ≥ 18 points. Analysis showed that in the elderly group, with the MCIRS-G scores increased, the blood system toxicity (P= ), liver and kidney function impairment (P=), fatigue (P=) in the different point have a significant
different incidence, but the incidence of digestive system toxicity (P = ) did not show significant differences. Trend test in the five points of elderly group,Ⅱ~ Ⅲ grade leucopenia rates were 0,%, 60%, %, 80% (P = ), liver and kidney
dysfunction rates were 0,0,20% , %, 60% (P = ), the incidence of fatigue were 0,%, 30%, %, % (P = ).With the increase of MCIRS-G score, the incidence of leucopenia, liver and kidney dysfunction and fatigue increasing. However, There was no change in the incidence of toxicity when stratified by age or KPS. MCIRS-G score was positively correlated with age (r = , P = ), and
was little correlated with KPS (r=,P= ).
orbidity was the