可移动罐和软管的在线清洗sop.doc

CIP SOP – NEW FORMAT
PURPOSE
Describe the procedure for the clean-in-place of portable tanks and flex hoses.
SCOPE
To all personnel that perform clean-in-place of portable tanks and flex hoses.
REFERENCES
OPE-2273 Operation of XXXX CIP Skids
RESPONSIBILITIES
Manufacturing is responsible for connecting portable tanks and flex hoses for cleaning.
DEFINITIONS
VP – Process Vessel with one 2” outlet
TNK – Process vessel with one 1½” outlet and one ½” outlet
MATERIALS REQUIRED
XXXX filter (10586)
XXXX Filter (10099)
CIP 100 (10089)
CIP 200 (10090)
SAFETY AND PRECAUTIONS
Ensure all appropriate warning signs are posted (Cell Culture Area) for CIP cycle.
CAUTION: Hot water and chemicals should be handled with care.
1. SAFETY TEXT & SYMBOL
Check equipment is not under pressure before removing any connections.
INSTRUMENTS AND EQUIPMENT
Process Flex Hoses
Utility Flex Hoses
Appropriate Connectors and Plugs
2. MANUAL TABLE OF CONTENTS
Portable Tank
PROCEDURE
SECTION
TABLE OF CONTENTS
PAGE
9.
Procedure
2

Tank Description & Flex Hose Classification
3

Preliminary Setup
4

Transfer Panel Connections (for CIP in adjacent room)
9

CIP plete Actions
11
3. INFORMATION TABLES - BACKGROUND
Tank Description & Flex Hose Classification
Summary of Portable Tank Types for CIP
TANK
CAPACITY (L)
NUMBER OF SPRAY BALLS
MAIN OUTLET VALVE SIZE
ADDITIONAL ½” OUTLET VALVE
(SECTION )
500
2
TNK - 1½”
VP - 2”
TNK only
250
1
TNK - 1½”
VP - 2”
TNK only
150
1
TNK - 1½”
VP - 2”
TNK only
100
1
TNK - 1½”
VP - 2”
TNK only
50
1
TNK - 1½”
VP - 2”
TNK only
40
1
TNK - 1½”
VP - 2”
TNK only
Flex Hose Classification for CIP
FLEX HOSE GROUP
FLEX HOSE
SIZE
CLEANED BY
Large Flex Hoses
1½”– 2”
CIP Skid
Small Flex Hoses
¾”– 1”
CIP Skid
½” flex hoses
½”
Glass wash
Possible Hook Up configurations
EQUIPMENT
CIP HOOK UP OPTIONS
Portable Tank
Direct to CIP Skid
Portable Tank
To CIP skid via Transfe