Trachoma and ocular surface disease Ophthalmology department of the second affiliated hospital, Chongqing medical university 彭艳丽 liyanli62@ 6/23/2018 1 Trachoma Summary It is chronic infective keratoconjunctivitis; It was epidemic and the first cause of blindness before the 1950s in our country; It declined dramatically after the 1970s and only appear in remote area now; 睑结膜 6/23/2018 2 1 2 7 upper palpebral conjunctiva upper fornical conjunctiva The ocular surface anatomy schematic diagram lower palpebral conjunctiva bulbar conjunctiva cornea bulbar conjunctiva lower fornical conjunctiva 6/23/2018 3 6/23/2018 4 6/23/2018 5 Trachoma Etiological factor Chlamydia (antigenic type A、B、C、or Ba) 6/23/2018 6 Trachoma Clinical manifestation 7 days, varies from 5-14 days children: insidious onset adults: acute or subacute 6/23/2018 7 Trachoma Clinical manifestation Three stages: Acute stage:Acute conjunctivitis Chronic stage:Inflammation subsidise, scarring and corneal pannus Advanced stage:All kinds plications and sequela, and even blindness. 6/23/2018 8 1. Acute stage symptoms Photophobia(畏光) tearing(流泪) foreign body sensation (异物感) Sticky secretion(分泌物) Trachoma 6/23/2018 9 1. Acute stage signs Hyperemia (充血) Papillar hypertrophy乳头增生 Follicle 滤泡 Corneal epithelitis (角膜上皮炎) Trachoma 乳头 滤泡 6/23/2018 10