pcg蛋白hpc2的生物信息学分析及其在不同hpv感染状态的宫颈癌细胞中的表达研究-妇产科（妇科肿瘤）专业毕业论文.docx

Bioinformatics of HPC2 and the expression of PcG protein
HPC2 in cervical carcinomas infected by different HPVs
Abstraet:
Objective:Cervical cancer is mon disease of women malignant tumor,it’S a serious threat to women’S life and a developing country, the new case rate of cervical cancer of china iS 30%of the
cancer patients have been growing at 2%to 3%a in recent maj ority of cervical cancer census showed the onset age tend to be there are a large number of studies have shown that HPV infection,especially the high-risk type HPV infection is the vast majority of the main cause of cervical precancerous lesions and cervical HPV 1 6 and HPV 1 8 are the mon gene(b group)is a new discovered cancer-related gene in recent evidence suggests that PcG plays an important role in the stability of homologous abnormity gene in Drosophila play S an critical role in embryonic development,tumor occurrence,tumor metastasis and maintaining stem a number of studies have shown that PcG is a oncogene, participating in nasopharyngeal carcinoma,breast cancer,lung cancer, bladder cancer and many other kinds of human tumor occurrence and is a member of the PcG gene family,and it is tested out that there is a lot of expression in a variety of existing studies have confirmed that the PcG protein HPC2 can induce cancer cell apoptosis,
3
万方数据
regulate cell growth, also had been confirmed that HPC2 is oVerexpression incervical pared with the normal cervical tissue,however the mechanism of HPC2 protein in cervical cancer is still unknown,needing further understanding and researching of HPC2 bioinformatics functions and its relationships with cervical cancer are needed,aiming to provide a new direction for the research of the pathogenesis of cervical cancer this experiment,use methods of bioinformatics, analyzing t