双源CT双能低剂量成像结合纯化单能谱技术在冠状动脉CT血管成像中的研究.doc新疆医科大学硕士学位论文 Dual source CT coronary artery imaging research with Dual energy and low bine with purifying single energy spectrum technique Postgraduate: Xiao HU Supervisor: Prof. Liu Wen ya Abstract Objective: Compare with standard prospective ECG gated and FBP reconstruction mode, analysis the coronary artery image quality and radiation dosage level of DSCT under dual energy with FBP and SAFIRE reconstruction. To evaluate the feasible of DSCT coronary artery imaging applying dual energy and low dose mode, to determine an appropriate keV level and optimize the scanning protocol. Methods: Continuous collection 80 cases, all the patients underwent DSCT coronary artery angiography examination. The patients were divided into control group (group A) and experimental group (group B) by using the table of random number. Group A (40 cases) performed DSCT coronary artery angiography exam by using prospective ECG gated scan mode. Group B (40 cases) used dual energy as the scanning method. According to the different reconstruction arithmetic model, group B was divided into two groups. Group B1 used FBP reconstruction model while group B2 applied SAFIRE reconstruction model. All the scanning data acquired were sent to the reprocessing workstation for further evaluation. All the data were measured by one doctor who was engaged in the diagnosis of coronary artery image for more than 5 years, and the image quality analysis and evaluation were performed by two senior radiologists. Image evaluation includes the axial image and curved reconstruction. Statistical analyses were performed after the data collected. Result: Group A: the heart rate 54~62 times/min, BMI was located between 24~28kg/m2. Objective evaluation for image quality: Aortic CT value=(±)HU, SD value= (±)HU, SNR value=(±), CNR value=(±). The subjective image quality score: (476±), radiation dose indexes CTDIvol (±) mGy, DLP (±) mGy *cm, ef