动物医学本科毕业论文1.doc

目录
摘要 1
1 材料与方法 3
试验材料 3
3
主要仪器 4
试验方法 4
4
5
2 测定丁酸钠微胶囊包埋率的方法 6
丁酸钠微胶囊包埋率计算公式 6
测定丁酸钠微胶囊含量的方法 6
6
6
6
最优方法的确立 6
3 结果与分析: 7
7
7
4 讨论 8
8
9
9
5结论 9
参考文献: 10
附录 11
谢辞 12
丁酸钠微囊制剂的最佳实验室制备工艺筛选研究
陈阳指导教师:姚刚
摘要:丁酸钠作为饲料添加剂广泛应用,主要作用于肠道,可提高动物采食量和日增重,但丁酸钠具有特殊的脂臭味,若直接饲喂,动物不采食。通过丁酸钠微囊制剂的工艺筛选研究,以喷雾干燥法丁酸钠微胶囊产品的包埋率为主要评价指标,对海藻酸钠浓度进行筛选,并优化了固形物浓度等喷雾干燥参数。结果表明最佳参数为:丁酸钠微胶囊适宜的壁材浓度为3%,固形物浓度为25%,PVP浓度为6%,乳化剂浓度为2%,搅拌档数为C档,进风温度 170℃,出风温度 85℃,搅拌时间为22分钟,蠕动泵50转每分钟,风机60,通针10。由实验筛选出的最优工艺参数测得丁酸钠的包被率在40%左右。
关键词:喷雾干燥法;丁酸钠;微胶囊;包被率
The optimization of the laboratory micro encapusulation techniques of butyrate as animal feed additives
Chen Yang Tutor:Yao Gang
Abstract:Sodium butyrate widely used as feed additive, main effect in the intestine, can improve the animal intake and sodium butyrate daily gain, but the fat has special odor, if direct feeding, animals do not feed themselves. Through the sodium butyrate millirod preparation technology screening study to spray drying sodium butyrate microcapsule product embedding rate as the main evaluation indexes, the concentration of sodium alginate screening, and optimize the solids concentration on the spray drying parameter. Results show the best parameters of sodium butyrate for: microcapsule appropriate wall material concentration of 3%, solids concentration is 25%, PVP concentration in 6%, emulsifier concentration of 2%, stirring file number as C files, into wind temperature 170 ℃, the air temperature 85 ℃, stirring time for 22 minutes, peristaltic pump 50 revolutions per minute, the fan to 60, the needle to 10. By experiment the optimal processing parameters were measured by sodium butyrate highest rate in the bag.
Key words: Spray drying; Sodium butyrate; microcapsule; Embedding rate

抗生素类作为促动物生长饲料添加剂的危害已被