替米沙坦与硝苯地平联合应用治疗高血压性心脏病的疗效观察.doc

替米沙坦与硝苯地平联合应用治疗高血压性心脏病的疗效
观察
崇州市第二人民医院四川成都611230
【】目的观察替米沙坦与硝苯地平联合应用治疗高血压性心脏病的临
床效果。方法选取入院2012年1月到2014年1月高血压性心脏病患者80例作为研究对象,随机分成两组分别为实验组和参照组,实验组患者应用替米沙坦与硝苯地平联合治疗,参照组患者应用硝苯地平联合单独治疗,24周的用药治疗后,对参照组和实验组治疗有效率和治疗前后的心率、LVEF值、血压的变化进行比较,并观察治疗后不良情况和死亡率。结果经过24周的治疗后,%,%。差异具有统计学意义(P < )。实验组患者在治疗前后的心率、LVEF值、血压的变化程度明显优于参照组患者,差异具有统计学意义(P < )。有4例出现不良情况,并不影响疗效,无死亡率。结论替米沙坦与硝苯地平联合应用治疗高血压性心脏病能更有效控制高血压性心脏病患者的血压,并能可逆转左室肥厚,疗效确切,安全可靠,值得在临床上推广。
【关键词】替米沙坦;高血压性心脏病;硝苯地平
Efficacy of telmisartan and bined treatment of hypertensive heart
disease
Abstract Objective:To observe the clinical effect of telmisartan and nifedipine
combined treatment of hypertensive heart : Selection have
admitted in January 2012 to January 2014 80 patients with hypertensive heart
disease as research subjects, they were randomly divided into two groups as the
experimental group and the reference group, patients in the experimental group use
telmisartan and bined therapy, the patient in reference group use nifedipine monotherapy, after 24 weeks of drug treatment, the reference group and
the experimental group before and after treatment efficiency and treatment of heart,
LVEF values, changes in blood pressure pared, and the adverse situation
observed after treatment and mortality. Result: After 24 weeks of treatment,
patients in the experimental group total e