多汗症.ppt

Hyperhidrosis
Dee Anna Glaser, .
Associate Professor
Vice Chairman
Department of Dermatology
Saint Louis University
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What is Hyperhidrosis?
Sweating that is more than required to maintain normal thermal regulation
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Sweating Nomenclature
Areas: Focal, regional, generalized
Symmetry: Symmetric or asymmetric
Classification: Primary vs. secondary
Type of sweating: Anhidrosis, euhydrosis, hyperhidrosis
Multi-specialty Working Group on Recognition, Diagnosis, and Treatment of Primary Focal Hyperhidrosis, 2003.
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Hyperhidrosis
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Causes of Generalized Hyperhidrosis
Usually secondary in nature
Drugs, toxins, substance abuse
Cardiovascular disorders
Respiratory failure
Infections
Malignancies
Hodgkin’s, myleoproliferative disorders, cancers with increased catabolism
Endocrine/metabolic disorders
Thyrotoxicosis, pheochromocytoma, acromegaly, carcinoid tumor, hypoglycemia, menopause
Rarely Idiopathic / Primary HH
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Causes of Localized Hyperhidrosis
Usually Idiopathic / Primary
Social anxiety disorder
Eccrine nevus
Gustatory sweating
Frey syndrome
Impaired evaporation
Stump hyperhidrosis after amputation
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Idiopathic (Primary) Focal Hyperhidrosis
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US Prevalence
Survey mailed to a representative sample of 150,000 US households in January 2002
Prevalence of hyperhidrosis in the US is % ( million individuals)
64% response rate
Approximately 6,800 respondents with hyperhidrosis
% of individuals with axillary hyperhidrosis (% of the US population or million people) have sweating that is barely tolerable and frequently interferes with their daily activities, or is intolerable and always interferes with their daily activities (based on the HDSS).
Projected to the US population
% have axillary hyperhidrosis: US prevalence is % (4 million individuals)
Strutton DR, Kowalski JW, Glaser DA, Stang PE. American Academy of Dermatology
61st Annual Meeting; March 21-26, 2003; San Francisco, Calif. Abstract P362.
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Mean Age of Onset