替代方案（Alternatives）之参考.ppt

替代方案(Alternatives)之參考
九-2 替代方案(Alternatives)
Search database (date, years, keyword, Search strategy, expert consult)
Phase 1 –Reduction and refinment
Provides prehensive view of field of study, including techniques mon species used, and may address unnecessary duplication.
Keyword Examples
Analgesic or sedative
Anesthesia
Housing or facility or caging or management
Welfare or well-being or pain or distress
Technique or procedure or method or assay
Phase 2 –Replacement
Address potential alternatives such as cell or tissue culture, models, simulations, animals lower on the ic scale.
Keyword Examples
Vitro or culture or artificial
Tissue or cell an
Virtual or simulation or digital or interactive
Fish or mollusk or cephalopod
Russell and Burch
Website
Assessing the Health andWelfare of Laboratory Animals(AHWLA)
/
USDA Animal Welfare Information Center (AWIC)

Altweb

UCDAVIS
.edu/Animal_Alternatives/
nc3Rs
The Johns Hopkins Center for Alternatives to Animal Testing (CAAT)

UCDAVIS
.edu/Animal_Alternatives/
Go3r
/
只是一篇導讀文章
未規定只能搜尋固定網站
Example 1 : 以database呈現
研究***物對rheumatoid arthritis 之療效,目前以collagen-induced arthritis (CIA) in rats and mice 及 adjuvant-induced arthritis (AIA) in rats等方法為主,均需使用動物,無法以體外模型替代。、.