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VITILIGOPPT讲座.ppt

文档分类：医学/心理学 | 页数：约10页举报非法文档有奖

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Whatisvitiligo?iclinkAffects1-2%ofpopulationDifficulttocureHarmfuleffects“Untreated”VitiligoAutoimmunedisorderMelanocytesdestroyed *Melanocyte-specificdifferentiation antigens *Tyrosinase,Dopachromeisomerase (TRP-2),gp100,MART-1ImmunoglobulinGrecognizesTRP-2,causing immuneresponsePossiblelinktocuringmelanoma?icLinksTwotypes-ature,multifactorialinheritanceAutosomalandnotlinkedtoraceorsexLinkedtootherautoimmunediseasesWeaklyheritableCuringVitiligoEffectsLonganddifficultprocess,rarely100%effectiveonindividualAlwaysinvolvessunlightorultravioletlightPhysicalandchemicalmethodsCosmeticsDepigmentationPsychologicalcounselingChemicalTreatmentOptionsforVitiligoCorticoidsPsoralens(PUVA)PhenylalanineP-aminobenzoicacid(PABA)Cantharidin,ablisterbeetlesecretionPhysicalTreatmentOptionsforVitiligoTattooing(micropigmentation)binationofSunandSunscreenReferences:“Anti-tyrosinase-relatedprotein-2immuneresponseinvitiligopatients…;” OkamotoT,IrieRF,FujiiS,etal.;TheJournalofInvestigative Dermatology;Dec1998; 111:1034-1039.“AutoantibodiestoTyrosinase-relatedprotein-1detectedinthesera…;”KempEH,WatermanEA, GawkrodgerDJ,etal.;BritishJournalofDermatology1998;139:798-805.“Asystematicreviewofautologoustransplantationmethodsinvitiligo;”NjooMD,WesterhofW,BosJD, BossuytPMM;ArchivesofDermatology,Dec1998134:1543-1549.“icsofvitiligoinKoreanpatients;”KimSM,ChungHS,HannSK;InternationalJournalof Dermatology1998;38:908

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