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TITLETowardsPersonalizedMedicineinMelanoma:ImplementationofaClinicalNext-#,MD,RosaMurriaEstal2#,PhD,GemaPérezSimó2,BSc,InmaculadadeJuanJimenez2,PhD,BegoñaEscutiaMuñoz1,MD,PhD,MercedesRodríguezSerna1,MD,PhD,VictorAlegredeMiquel3,MD,PhD,MargaritaLlavadorRos4,MD,RosaBallesterSánchez5,MD,EduardoNagoreEnguídanos6,MD,PhD,SaraiPalancaSuela2*†PhD,RafaelBotellaEstrada1*,MD,PhD.#co-authors(contributedequallytothemanuscript)*co-seniorinvestigators†Correspondenceshouldbeaddressedtopalanca_******@gva.******@1DepartmentofDermatology,icLaFe,Valencia(Spain).2MolecularBiologyLaboratory,ServiceofClinicalAnalysis,icLaFe,Valencia(Spain).3DepartmentofDermatology,HospitalGeneralUniversitariodeValencia,Valencia(Spain).4DepartmentofPathology,icLaFe,Valencia(Spain).5DepartmentofDermatology,LaPlanaHospital,Villarreal,Castellón(Spain).6DepartmentofDermatology,DepartmentofDermatology,InstitutoValencianodeOncología,Valencia(Spain).SUPPLEMENTARYINFORMATIONSupplementarytable1(panyingExcelfile“TableS1–Pathogenicvariants”)Supplementarytable2(panyingExcelfile“TableS2–Custompaneldesign”)FigureS1FigureS1:,%%1%%2%25%FigureS2: