清华大学XX年生物化学1本科期末考试试题(同名46159).doc

--------------------------校验:_____________-----------------------日期:_____________清华大学XX年生物化学1本科期末考试试题(同名46159)清华大学XX年生物化学1本科期末考试试题考试科目:生物化学考试时间:考试类型::howmanycarbonsdoesArachidicacidhave?(20carbons)2:howmanydoublebondsdoesArachidonicacidhave?(4doublebonds)3:listtwoadvantagesthatfatshaveoversugarsasstoredfuels(ram;nohydrationneeded)4:whereinsidethecellsaremostofthephospholipidsdegraded(lysosomes)5:?(glycosphingolipidsorlipidsandsurfaceproteins)6:umulationofmembranelipids(Tay-Sachs,Sandhoff’s,Fabry’s,Gaucher’s,orNiemann-Pickdiseases)7:listthethreemaineicosanoidsthatproducedfromarachidonicacid(prostaglandins;thromboxanes;andleukotrienes).8:listoneNASIDyouknow(aspirin,ibuprofen,oracetaminophenormeclofenamate)9:listtwofat-solublevitamins(A,D,E,K)10:whichvitamincanbederivedfrombeta-carotene(A).11:whichyearwasthefluidmosaicmodelproposed?(1972)12:whythethicknessofmostbiologicalmembranesisthickerthan3nm,thestandardthicknessoflipidbilayer?(duetoassociationofproteinstothemembraneandcarbohydratesonthemembrane)13:hetransitiontemperatureofthelipidbilayer(thetemperatureabovewhichtheparacrystallinesolidchangestofluid)14:IfamembraneproteinhasitsN-terminusexposedtotheoutsideofthecellwhileitsC-partment,isitatypeItransmembraneprotein?(yes).15:Howcanyoupredictifaproteinhasatransmembranedomain?(hydropathyorhydropathyindex,orhydropathyplot).16:R5andCD4).17:FortheNa+K+ATPase,howmanyNa+andK+canitmoveacrossthemembraneforthehydrolysisofoneATP(2K+in,3Na+out).18:whatdrivesF-typeATPasestosynthesizeATP?(protonorprotongradients)19:Theacetylcholinereceptorisa_____-gatedchannel(Ligand)20:TheneuronalNa+channelisa_____-gatedchannel(voltage)(3points)plementarystrandsinduplexDNAwaselegantlydeterminedin1960byArthurKornbergbynearest-,DNAissynthesizedbyDNApolymeraseIfromone(alpha-32P)-