应用薄层色谱对牛磺酸生产工艺进行流程诊断.doc

应用薄层色谱对牛磺酸生产工艺进行流程诊断应用薄层色谱对牛磺酸生产工艺进行流程诊断第4期汤志刚,等:应用薄层色谱对牛磺酸生产工艺进行流程诊断17Synthesisof2-AllylEsterofCyclohexanoloxyaceticAcidDENGShu—hua,ZHOULi—qinN,CHENGXiao-ling(Departmento,ChemicalEngineering,GuangdongUniwersityof7,Guangzlwu510090,?)Abstract:Sodiumcyclohexanoloxyacetatewassynthesizedbylmol:[coholatetOs()diumchlomacetateat135,145?%ThesodiumcyclohexanoloxyacetateW&qacidifiedbyHC1togettheintermediateproduct,2--p—%Theoptimalmoleratiowasacid:alcohol=1:,,whiletheoptimalreactiontemperaturewas115,120?andthereactiontimewas6hKeywords:2-cyclohexanoloxyaceticacid;ally1alcohol:esterlfication;2一ally1~,,/z]【战0084)v-g1000842_7,.1/IJ(/'}fc摘要:以硅胶G为固定相,,反应原料乙醇***:冰醋酸:乙醇:水:8:2:1:l(体积比)对,,分析了原料,酯化反应产物,还原反应产物,,酯化反应,还原反应,粗结晶和结晶精制各步收率分别为8957%,7695%,%%,:塑蛰;堂墨j苣蹬;越;型堕芝工,中图分类号::A文章编号:1003—5214(1999)04—0017—03牛磺酸是一种重要的强化营养剂...,目前生产工艺存在的最大问题是收率仅6O%左右,,多数生产企业缺乏必要的生产流程分析手段,很难判断牛磺酸收率的"瓶颈"步骤,