齐拉西酮与阿立哌唑治疗以阴性症状为主的精神分裂症对照研究.doc

齐拉西酮与阿立哌唑治疗以阴性症状为主的精神分裂症对照研究.doc齐拉西***与阿立哌呼治疗以阴性症状为主的精神分裂症对照研究齐拉西***与阿立哌哩治疗以阴性症状为主的精神分裂症对照研究【摘耍】目的比较齐拉西***与阿立哌哩治疗以阴性症状为主的精神分裂症的疗效和安全性。方法将66例以阴性症状为主的精神分裂症患者随机分为研究组(齐拉西***治疗)和对照组(阿立哌哩治疗),采用阳性和阴性症状量表(PANSS)、阴性症状评定量表(SANS)评定疗效,副反应量表(TESS)评定不良反应。结果治疗8周后,齐拉西***%,%%,%o齐拉西***%,%。结果显示两组在疗效和不良反应发生率方面差异均无显著性(P>%)o结论齐拉西***与阿立哌陞治疗以阴性症状为主的精神分裂症疗效相当,不良反应轻微,两种药物均有疗效好、安全性高的特点。【关键词】齐拉西***;阿立哌陞;精神分裂症;parativeStudyofZiprasidoneandAripiprazoleintheTreatmentofSchizophreniawithPredominant!yNegativeSymptoms・LiuWei,ZhangXueping・TheThirdPeople'sHospitalofHeze,Heze274031,[Abstract]paretheefficacyandthesafetyofZiprasidonewithAripiprazoleintreatingschizophreniawithpredominantlynegativesymptoms・Methods66schizophreniainpatientswithpredominantlynegativesymptomswererandomlyassignedtoZiprasidonegroupandAripiprazolegroup・Al1ofthecasesweretreatedwithZiprasidoneorAripiprazolefor8weeks・TheefficacyandsideeffectswereevaluatedwithPANSS,SANSandTESS・%%%%inAripiprazolegroup・Thereisnosignificantdifferencebetweenthetwogroups(卩>).%%(P>0・05).ConclusionTheresultssuggestedthatZiprasidonewasaseffectiveasAripiprazoleinthetreatmentofschizophreniawithpredomina