AIDS ine Research英文资料.pdf

ISBN: 0-8247-0645-5 This book is printed on acid-free paper. Headquarters Marcel Dekker, Inc. 270 Madison Avenue, New York, NY 10016 tel: 212-696-9000; fax: 212-685-4540 Eastern Hemisphere Distribution Marcel Dekker AG Hutgasse 4, Postfach 812, CH-4001 Basel, Switzerland tel: 41-61-261-8482; fax: 41-61-261-8896 World Wide Web http:/ / publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales/Professional Marketing at the headquarters address above. Copyright ? 2002 by Marcel Dekker, Inc. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, micro?lming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher. Current printing (last digit): ********** PRINTED IN THE UNITED STATES OF AMERICA Preface There is perhaps no greater need in medical science at the inception of the 21st century than the development of a preventive ine against HIV (see Chapter 1, by Gary Nabel). It seems paradoxical that a human pathogen that medical science knows more about than virtually any other causative agent remains with- out a solution (Chapter 2, by Oren Cohen and Anthony Fauci, provides insight into this statement). Yet, we can draw from many analogies. We may understand everything about a mountain but not be able to reach its summit until there is a new technological advance. Is that the current situation with AIDS? Do we have the essential information and multiple tempting pathways but no pass to reach the top? Or is a major piece of information missing? There is no way for us to give an honest answer. It is possible that a partially—or pletely— essful preventive ine against HIV will be developed within the next ?ve years, but it is also possible that this will never be achieved. However, reality is likely to lie somewhere between these two extreme predic