宫颈细胞刷取材：传统涂片与液基涂片的比较分析.doc

宫颈细胞刷取材：传统涂片与液基涂片的比较分析.doc宫颈细胞刷取材:传统涂片与液基涂片的比较分析作者:谭学君,黄光炜,叶丽群【摘要】目的改进传统宫颈细胞学的取材方式,用宫颈细胞刷取材,比较传统涂片与液基涂片在宫颈癌筛查中阳性细胞检出率的差异。方法用上述两种方法进行宫颈癌筛查,TBS系统诊断报告。细胞阳性的病人行***镜下病理活检。SPSS软件包分析结果。结果两种不同的制片方法细胞学阳性率未明确诊断意义的非典型鳞状上皮细胞(ASC-US及以上)为:%(63/1007),%(75/1075),两种制片方法对宫颈癌筛查中阳性细胞的检出率差异无显著性。细胞学阳性者与病理活检诊断结果符合率均较高(P<)o结论液基细胞学的问世,只是制片技术的重大革新,但不能完全替代人工的经验判读且成本低的传统涂片方法。【关键词】宫颈细胞刷;宫颈疾病/诊断;***涂片;液基涂片Abstract:ObjectiveToimprovethecol1ectiondevicesforobtainingcervicalsamples・paredbetweenconventionalsmearsandliquid~・2007andtheTBSdiagnosissystemwasusedtoreportthelaboratoryresults・Thecolposcopyfollowingtheorm&lityofsmears・-USwere:%(63/1007)ofconventionalsmears,%(75/1075)of1iquid-,therewerenostatisticallysignificantdifferences・Thecoincidentratebetweentheresultofpatientswithabnormalcytologyandthatofpatho1ogica1diagnosiswashigh(P&It;)・ConclusionTheliquid-basedcytologyisaninnovationforpreparationtechnique,pletelyreplacehumanexperiencereadingaswellaslow-costtraditionalsmearstechnique・Keywords:cytobrush;cervixdisease/diagnosis;vaginalsmears;1iquid-baseds