广州管圆线虫病免疫诊断研究进展.doc

广州管圆线虫病免疫诊断的研究进展广州管圆线虫病免疫诊断的研究进展2006??12?3(?~?%67?h)???(????33,????,?????2?~???????????h?????t???RS0#?-?????(xx_@???????7??????(Angiostrongyliasiscan-tonensis)?I???????????????????m???h????S0???I???????7????[Angiostrongyluscan-tonensis(Chen,1935)Dougherty,1946]?@?0?????~,?????????????A????????????????,?~???????.??????????,?r???????m?????????-?m?i?????y?????m?????????-?m?i???i??(Eosinophilic-meningitisorMeningoen-cephalitis,EM),???????mS0???????7???????~???K?????[?????S?;?????-?d???x????,?.?????????????-S01996?????????M?.???m?Z?;???????h????,??10?????:?????????7?????.?????~??????S2?g?????????M?i???????S?;?m???K??,???#?????????#?????h?e???~?A?A?v,???????????7???????????M?1?S?????y?????K??,?????l???????h???m????(Emerginginfectiousdiseases)[1]S0?????l???????0?i?????M???????r?????????7???????????K??,???h???????l?-,???????m,?g?;?E???????????h????S0???b???????????I???????7????????????????,?Z?I?i?#???.???????????;??????(<10%),?;?????W????????????????,?????y???(?????????7?????????????????????m???t??,????????????S01?????????????????????????T?B????(ELISA):???M1982??,CrossJH?z[2]???%4?h?????b?)?????MELISA??????16??EM?????R?(,?v?&?J?m????S0???n?_[3]?z???MELISA????22???f?????????7?????????(?R?(?????H??,???(???????H???A??????????S2?????????????????0?,???T?N???m?n?z(P<)S0???g?-[4]?z?MELISA???????@?_???h???(?R?(????,????????1?d?3???(?????h?m????(%),???,???h???????H?????M???-ELISA:?:???H?z[5]?????m?g?????????MDot-ELISA?????h???m?9?R?(,?J?m???;100%,?A?d?????h???9?R?(?,10%??????????S0EamsobhanaP?z[6]???????P?????y??31kDa?????;????????Dot-ELISA????,????10?????????7?????????R?(S260?????????h????????20?????????R?(,???h?m?????0?m?v?;100%,???t?b?gDot-ELISA???????7?????????????W,???-?d??????????????,???h?m?????0?m?v?;100%,?_?t???????s,?@?????????????),???M?h?M6?d?3???#,3?n????????????,???T?0?3???;???M[7]??????????????(IEST):?????7?z[8]?M?g???????)?v?????????????????R?(????,?h???m?9?J?m???????;84%,?????9?R?(?v?;?H?m,???A???????,?????????h?m????