asiatic acid and maslinic acid attenuated kainic acid-induced seizure through decreasing hippocampal inflammatory and oxidative stress外文.pdf

Epilepsy Research 139 (2018) 28–34
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Asiatic acid and maslinic acid attenuated kainic acid-induced seizure
through decreasing hippocampal inflammatory and oxidative stress T
⁎ ⁎
Zhi-hong Wanga, , Mei-chin Monga, Ya-chen Yanga, Mei-chin Yina,b,
a Department of Food Nutrition and Health Biotechnology, Asia University, Taichung City, Taiwan
b Department of Medical Research, China Medical University Hospital, China Medical University, Taichung City, Taiwan
ARTICLE INFO ABSTRACT
Keywords: Seizure is a neurological disorder including hippocampal oxidative and inflammatory stress, and glutamate
Asiatic acid toxicity. Thus, any agent(s) that mitigate(s) these events in hippocampus might attenuate seizure severity. The
Maslinic acid effects of asiatic acid (AA) or maslinic acid (MA) pre-administration at 20 or 40