the role of autophagy in the intracellular survival of campylobacter concisus论文.pdf

FEBS Open Bio 4 (2014) 301–309
journal homepage:
The role of autophagy in the intracellular survival of Campylobacter
concisus
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Jose A. Burgos-Portugal, Hazel M. Mitchell, Natalia Castaño-Rodríguez, Nadeem O. Kaakoush
School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW 2052, Australia
article info abstract
Article history: Campylobacter concisus is an emerging pathogen that has been associated with gastrointestinal dis-
Received 7 January 2014 eases. Given the importance of autophagy for the elimination of intracellular bacteria and the sub-
Revised 3 March 2014 version of this process by pathogenic bacteria, we investigated the role of autophagy in C. concisus
Accepted 13 March 2014
intracellular survival. Gentamicin protection assays were employed to assess intracellular levels of C.
concisus within Caco-2 cells, following autophagy induction