该论文来源于网络,本站转载的论文均是优质论文,供学****和研究使用,文中立场与本网站无关,版权和著作权归原作者所有,如有不愿意被转载的情况,请通知我们删除已转载的信息,如果需要分享,请保留本段说明。 [摘要] 目的 觀察硝苯地平辅助治疗对妊娠高血压患者凝血酶与心功能的影响。 方法 方便选取该院2017年5月—2019年9月收治的112例妊娠期高血压患者随机分为参照组与联合组,各56例,给予参照组拉贝洛尔治疗,联合组在拉贝洛尔的基础上加用硝苯地平治疗。比较治疗前后两组凝血酶指标[凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、纤维蛋白原(FIB)]、心功能指标[血清肌钙蛋白(cTnT)、血浆脑钠肽(BNP)]水平变化。 结果 治疗前,两组上述指标水平差异无统计学意义(P>);治疗后,两组PT、APTT水平均显著升高,联合组[PT(±)s、APPT(±)s]显著高于参照组[PT(±)s、APTT(±)s],差异有统计学意义(t=、,P<);两组FIB、cTnT、BNP水平均较治疗前显著下降,联合组[FIB(±)g/L、cTnT (±)ng/mL、BNP(±)pg/mL]显著低于参照组[FIB(±)s、cTnT(±)ng/mL、BNP(±)pg/mL],差异有统计学意义(t=、、,P<)。 结论 硝苯地平辅助治疗对妊娠高血患者凝血功能与心功能改善效果显著,有一定临床运用价值。 [关键词] 硝苯地平;妊娠期高血压;凝血酶;心功能 [中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2020)10(b)-0094-03 [Abstract] Objective To observe the effects of adjuvant nifedipine treatment on thrombin and heart function in patients with pregnancy-induced hypertension. Methods 112 patients with hypertension during pregnancy admitted to the hospital from May 2017 to September 2019 were randomly divided into a reference group and a combination group, 56 cases in each group. The reference group was treated with labetalol, and the combination group was in Labbe Nifedipine was added to Lolol. Compare the two groups of thrombin indexes before and after treatment[prothrombin time (PT), activated partial prothrombin time (APTT), fibrinogen (Fib)], cardiac function indexes [serum troponin (cTnT), plasma brain sodium Peptide (BNP)] level changes. Results Before treatment, there was no statistically significant difference in the above index levels between the two groups (P>). After treatment, the PT and APTT levels of the two groups increased significantly, the combination group[PT(±)s, APTT (±)s] was significantly higher than the reference group [P