高钾危害.pptx

The influence of high Kaliumconcentrationmade by ZhangJie*ExcitabilityC(K+) ↑(5-7mmol/L)→ K+ outflow↓→ resting potential↓→excitability↑→ C(K+) ↑(>7-9mmol/L)→partial Na+ channelinactivation→ Na+ inflow↓→excitability↓→asystole*auto-rhythmicityC(K+) ↑→auto-rhythmicity cell membrane K+ permeability↑→K+ outflow↑、 Na+ inflow↓→auto-depolarization↓→ auto-rhythmicity↓*conductivity C(K+) ↑→resting potential↓→phase 0 velocity of depolarization↓、range↓→velocity of excitation conduction↓→ conductivity*ContactivityC(K+) ↑→①Ca2+ inflow↓→②Na+——K+ pump activation → extracellular FluidC(Na+)↑→Na+/Ca2+ exchange↑→Ca2+ outflow↑①②→intracellular FluidC(Ca2+)↓→contactivity↓*Cardiogram? Thank you.? Refer to physiopathology