中国现代药物应用2022年1月第16卷第1期 Chin J Mod Drug Appl, Jan 2022, Vol. 16, No. 1 ·121· 阿托伐他汀ctions. Results The total effective rate of treatment % in the observation group was higher than % of the control group, and the difference was statistically significant (P<). After treatment, the TC, TG, and LDL-C of the two groups were lower than those of this group before treatment, and the HDL-C washigher than that of this group before treatment; the TC (±) mmol/L, TG (±) mmol/L, LDL-C (±) mmol/L of the observation group were lower than (±), (±), (±) mmol/L of the control group, and the HDL-C (±) mmol/L was higher than (±) mmol/L of the control group. All the differences were statistically significant (P<). The incidence of adverse reactions % in the observation group was lower than % in the control group, and the difference was statistically significant (P<). Conclusion Compared with simvastatin, atorvastatin has a higher therapeutic effect in the treatment of hyperlipidemia, and can improve the relevant blood lipid indicators with fewer adverse reactions and higher safety, which can be promoted. 【Key words】 Atorvastatin; Simvastatin; Hyperlipidemia; Therapeutic effect 高脂血症的发生机制比较复杂 , 与脂肪代谢异常