: . World Corresponding author. E-mail address: ******@ (J.-)
Keywords: Post-stroke cognitive impairment Acupuncture Four seas theory Abstract Objective: To observe the clinical effect on post-stroke cognitive impairment (PSCI) treated by acupuncture at the acupoints composed in accordance with the "four seas theory". Methods: A total of 70 patients with PSCI were randomly divided into a treatment group (n=35) and a control group (n=35). In the control group, conventional basic treatment and rehabilitation training were adopted, while in the treatment group, on the base of the treatment as the control group, acupuncture was applied at the acupoints composed in accordance with "four seas theory", lasting 8 weeks. The scores of mini-mental state examination (MMSE) and the instantaneous memory, the scores of Montreal cognitive assessment (MoCA) and the delayed memory, the score of kidney essence insufficiency in syndrome differentiation scale of vascular dementia (SDSVD), event-related potentials (ERP) P300 and clinical therapeutic effect were compared in the patients between two groups before and after treatment separately. Results: After treatment, MMSE score and the score of instantaneous memory were higher than the results before treatment in either group respectively (all P < ), in which, MMSE score in the treatment group was higher than that in the control group (P < ). After treatment, MoCA score and the score of delay recall were higher than the results befo