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肺癌伴肺部感染患者痰标本病原分布及药敏试验分析.pdf


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2022年 3 月              中国民康医学 Mar.,2022
第 34 on who were admitted to our hospital from May 2017 to May 2020
were selected as the research objects. The bacteriology detection was performed on the sputum specimens. Then, the pathogen distribution and the
drug sensitivity test results were analyzed. Results: 98 pathogenic bacteria were detected in the 85 patients, including 52 (%) gram-negative
bacteria, 29 (%) gram-positive bacteria and 17 (%) fungi. Among the major gram-negative bacteria, Escherichia coli and Pseudomonas
aeruginosa had higher resistance rates to Ampicillin, Cefazolin, and Ceftriaxone (all >80%), and were highly resistant to Imipenem, Ceftazidime, and
Meropenem. Among the major gram-positive bacteria, Staphylococcus aureus and Staphylococcus haemolyticus were 100% resistant to Penicillin and
Ampicillin, and were only highly sensitive to the third-line antibiotics Vancomycin and Linezolid. Fungal susceptibility tests showed that Candida
albicans had a high resistance rate to the first-line antifungal drug Ketoconazole. Conclusions: The pathogen distribution in the sputum specimens
from the patients with lung cancer and pulmonary infection is mainly gram-negative bacteria, followed by gram-positive bacteria and fungi. The
main pathogens are generally resistan

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