n-3脂肪酸对外科术后SIRS患者阻断过度炎症反应的作用 外科患者术后护理体会.docx

n-3脂肪酸对外科术后SIRS患者阻断过度炎症反应的作用_外科患者术后护理体会
　　033100山西方山县人民医院1 　　030001山西医科高校第一附属医院2 　　摘 要 目的：探讨n-3脂肪酸对外科全身炎症反应综合征100ml,and the other twenty-four cases in control group were not patients were observed for 5 data about inflammatory parameter were measured and analyzed,respectively,1 day before TPN and 5 days after the acute physiology has also been respectively :No side effects were scores of acute physiology the level of serum CRP,IL-1,IL-6,IL-8,TNF-α decreased significantly in two groups （P＜）,but the decrease in n-3 fatty acids group was more obvious than that in control group （P＜）.Conclusion:N-3 fatty acids could relieve the degree of acute inflammatory response of the surgical postoperative patients with SIRS,and benefit to resume the function of cells and organs. 　　Key Words n-3 fatty acids；TPN；SIRS 　　资料与方法 　　全部病例均来源于山西医科高校附属一院2009年8～11月，普外科住院术后危重症患者。将符合SIRS诊断标准：1992年美国胸内科医师学会和危重症医学会联席会议制定［1］：①体温＞38℃或＜36℃；②心率＞90次/分；③呼吸＞20次/分或PaCO2＜32mmHg；④WBC＞12×109/L或＜×109/L或无趣白细胞＞10%，具有两项或两项以上特征的患者即可诊断SIRS的48例患者作为本课题的探讨对象，采纳前瞻、随机、比照的临床探讨，应用随机表方法将患者随机分为试验组（含n-3脂肪酸的TPN）和比照组（不含n-3脂肪酸的TPN）。两组病人一般资料，其年龄、性别、构成、体重两组病人之间比较差异无统计学意义（P＞）。 　　结 果 　　炎症反应指标两组治疗后第5天CRP、TNF-α、IL-1、IL-6、IL-8等指标与治疗前相比均有降低（P＜）；各指标两组间比较，治疗前都无统计学差异（CRP，；TNF-α，；IL-1，；IL-6，；IL-8，），治疗后第5天差异有统计学意义（CRP，；TNF-α，；IL-