Journal of Diabetes and plications 28 (2014) 553–558
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Journal of Diabetes and plications
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Cost implications of the use of basal insulin glargine in people with
early dysglycemia: The ORIGIN trial☆,☆☆
A. Lamy a,b,c,d,⁎, W. Tong a,b, H. Jung a, A. Gafni d,f, K. Singh g,h, J. Tyrwhitt a, S. Yusuf a,d,e,
. Gerstein a,e on behalf of the ORIGIN Investigators
a Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
b CADENCE Research Group, Hamilton Health Sciences, Hamilton, Ontario, Canada
c Department of Surgery, McMaster University, Hamilton, Ontario, Canada
d Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
e Department of Medicine, McMaster University, Hamilton, Ontario, Canada
f Centre for Health Economics and Policy Analysis, McMaster University, Hamilton, Ontario, Canada
g All India Institute of Medical Sciences, New Delhi
h Centre for Chronic Disease Control, New Delhi
article info abstract
Article history: Aims: The cost implications of the e Reduction with an Initial Glargine Intervention (ORIGIN) trial
Received 27 August 2013 were evaluated using a prespecified analysis plan.
Received in revised form 31 January 2014 Methods: Purchasing power parity-adjusted country-specific costs were applied to consumed healt
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