Mitogen-Activated Protein Kinase Inhibition Reduces Mucin2 (Muc2) Production and Mucinous Tumor Growth.pdf.pdf

Accepted Manuscript
Mitogen-Activated Protein Kinase Inhibition Reduces Mucin2 (Muc2) Production and
Mucinous Tumor Growth
Ashok K. Dilly, Xinxin Song, PhD, Herbert J. Zeh, MD, Z. Sheng Guo, PhD, Yong J.
Lee, PhD, David L. Bartlett, MD, Haroon A. Choudry, MD
PII: S1931-5244(15)00107-3
DOI: .
Reference: TRSL 892
To appear in: Translational Research
Received Date: 28 December 2014
Revised Date: 17 March 2015
Accepted Date: 24 March 2015
Please cite this article as: Dilly AK, Song X, Zeh HJ, Guo ZS, Lee YJ, Bartlett DL, Choudry HA, Mitogen-
Activated Protein Kinase Inhibition Reduces Mucin2 (Muc2) Production and Mucinous Tumor Growth,
Translational Research (2015), doi: ..
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ACCEPTED MANUSCRIPT
1

MITOGEN-ACTIVATED PROTEIN KINASE INHIBITION REDUCES MUCIN2
(MUC2) PRODUCTION AND MUCINOUS TUMOR GROWTH
Ashok K. Dilly1, Xinxin Song PhD1, Herbert J. Zeh MD1, Z. Sheng Guo PhD1, Yong J. Lee
PhD1,2, David L. Bartlett MD1, Haroon A. Choudry MD1
1Department of Surgery, 2Department of Pharmacology & Chemical Biology, University of
Pittsburgh Medical Center, Pittsburgh PA 15213
All correspondence should be addressed to Dr. Haroon A. Choudry, Department of Surgery,
University of Pittsburgh, Hillman Cancer Center, 5150 Centre Avenue, Suite 414, Pittsburgh, PA
15232, ., Tel 1-(412) 692-2852, Fax (412) 692-2520, Email: ******@
Short Title: Inhibiting MUC2 by targeting MEK-ERK pathway
Key Words: mucin; MUC2; RDEA119; xen