groove pancreatitis(沟槽状胰腺炎).pdf

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AJR Am J Roentgenol. Author manuscript; available in PMC 2014 April 30.
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AJR Am J Roentgenol. 2013 July ; 201(1): W29–W39. doi:.9956.
Groove Pancreatitis: Spectrum of Imaging Findings and
Radiology-Pathology Correlation
Siva P. Raman1, Safia N. Salaria2, Ralph H. Hruban2, and Elliot K. Fishman1
1Department of Radiology, Johns Hopkins University School of Medicine, JHOC 3251, 601 N
Caroline St, Baltimore, MD 21287
2The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of
Medicine, Johns Hopkins Medical Institutions, Baltimore, MD
Abstract
OBJECTIVE—Groove pancreatitis is a rare form of chronic pancreatitis affecting the “groove”
between the pancreatic head, duodenum, mon bile duct. The exact cause is unknown,
although there are strong associations with long-term alcohol abuse, functional obstruction of the
duct of Santorini, and Brunner gland hyperplasia.
CONCLUSION—Unfortunately, differentiating groove pancreatitis from malignancy on the basis
of imaging features, clinical presentation, or laboratory markers can be extraordinarily difficult,
and the vast majority of these patients ultimately undergo a pancreaticoduodenectomy (Whipple
procedure) because of an inability pletely exclude malignancy. In certain cases, however,
the imaging features on CT and MRI can allow the radiologist to prospectively suggest the correct
diagnosis.
Keywords
CT; groove pancreatitis; MRI; pancreatic adenocarcinoma; pancreatic cancer
Groove pancreatitis, a rare form of chronic pancreatitis affecting the “groove” between the
superior aspect of the pancreatic head, the duodenum, and mon bile duct, was first
described by Becker in 1973 [1] and has remained a diagnostic dilemma for radiologists,
pathologists, and clinicians since its first description [2,