再次麻疹的发病特点和免疫学机制论文.doc

再次麻疹的发病特点和免疫学机制论文.doc再次麻疹的发病特点和免疫学机制论文
.freelanifestations and immunological mechanism in patients easles
【Abstract】 Objective To study the clinical manifestations and immunological mechanism of second 36 cases easles munological condition and clinical patients ildly typical (MT)and the mildly atypical (MAT) -measles virus (MV) IgM,IgG and anti-rubella IgM in serum al people easles history contacted closely easles (1)The age 13~16 yrs easles onths al people respectively,and differentiation arked bet(P ). Of 36 MT and MAT measles isdiagnosed easles,and ≥1:400 als easles onths may catch second after 13 years old. (2)Second measles is very easy to be misdiagnosed because atypical manifestation and have a measles history,and a anti-MV IgM test is necessary for the diagnosis.(3)Catch measles and degrees of the disease mainly dependent on anti-MV IgG level.

【Key easles;clinical manifestation;immune

麻疹,这一对人类危害大而持久的传染病,在广泛实施计划免疫的今天,其发病率已明显下降[1],但***及不典型麻疹的发病比例则明显增加[2],尤其是再次麻疹,因其曾患过麻疹及临床表现不典型而每造成误诊或漏诊[3]。然而,人们对再次麻疹的发病特点所知甚少,对再次麻疹患者的临床表现与抗-麻疹病毒(MV)Ig***平的关系亦鲜有所知。本文分析了36例再次麻疹患者的临床表现及其与抗-MV Ig***平的关系,以期了解再次麻疹的发病特点及其免疫学机制,进而为及时诊断和采取防控措施、减少因麻疹引起的其他疾病[4]提供理论依据。
1 对象与方法

对象从1999年3月~2005年12月连续收治在两所医院诊治的再次麻疹患者36例,%。其中男20例(%),女16例(%);~27岁,。所有患者均排除了皮肤过敏或其他皮肤疾病。

临床分型根据患者的临床表现及病情程度按以前的方法分