该【核因子-kB介导小鼠ARDS中性粒细胞聚焦调控机制及PDTC干预作用研究的中期报告 】是由【niuww】上传分享,文档一共【2】页,该文档可以免费在线阅读,需要了解更多关于【核因子-kB介导小鼠ARDS中性粒细胞聚焦调控机制及PDTC干预作用研究的中期报告 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。核因子-kB介导小鼠ARDS中性粒细胞聚焦调控机制及PDTC干预作用研究的中期报告我将为您翻译这篇中期报告的英文翻译版:IntermediateReportontheStudyoftheRegulationMechanismofNeutrophilAggregationinMouseARDSMediatedbyNuclearFactor-kBandtheInterventionEffectofPDTCIntroduction:Acuterespiratorydistresssyndrome(ARDS)-kB(NF-kB)isinvolvedintheinflammatoryresponseandregulatestheexpressionofmanycytokines,chemokines,adhesionmolecules,,weaimtoinvestigatetheregulatorymechanismofNF-kBinneutrophilaggregationandtheinterventioneffectoftheNF-kBinhibitorpyrrolidinedithiocarbamate(PDTC):C57BL/6micewererandomlydividedintofourgroups:controlgroup,ARDSgroup,PDTCinterventiongroup,(LPS).,-kB,intercellularadhesionmolecule-1(ICAM-1),tumornecrosisfactor-α(TNF-α),andinterleukin-6(IL-6)weremeasuredbyWesternblotandquantitativereal-:essfullyestablished,-kB,ICAM-1,TNF-α,andIL-6weresignificantlyup--kB,ICAM-1,TNF-α,andIL-,:NF---kBmaybeapotentialtherapeutictargetforARDS,andPDTCmaybeapromisingdrugforthetreatmentofARDS.
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