法舒地尔治疗有机磷农药中毒的临床观察.pdf

中国现代医药杂志 2010 年 7 月第 12 卷第 7 期 MMJC, Jul 2010, Vol 12,
·13 ·
法舒地尔治疗有机磷农药中毒的临床观察
赵宁军燕宪亮卓晓英梁高永许铁
探讨法舒地尔激酶抑制剂对有机磷农药中毒迟发性神经病发病率的影响以及对其
【摘要】目的(Fasudil,Rho ) ,
治疗作用对例重度有机磷农药中毒患者随机分为对照组和治疗组两组均给予阿托品盐酸戊乙奎醚及***解
。方法 80 , , 、
磷定等综合治疗治疗组在此基础上给予应用静脉滴注对两组患者的临床表现发病率进行分析观察两组患者
, Fasudil , 、,
临床表现神经电生理变化判断临床疗效治疗组患者迟发性神经病发生率低于对照组
、, 。结果 Fasudil (P<);Fasudil
能改善患者的神经功能临床应用法舒地尔治疗有机磷农药中毒能降低迟发性神经病的发生率并能有效治疗该
。结论,
病
。
有机磷农药中毒迟发性神经病法舒地尔
【关键词】
Clinical observation on the therapy of fasudil anophosphorus insecticides poisoning Zhao Ningjun,Yan Xian-
liang,Zhuo Xiaoying, et al. Department of Emergency Care, Anaesthetic College of Xuzhou Medical College,Emergency Center
of the Affiliated Hospital of Xuzhou Medical College,Xuzhou 221004
【Abstract】 Objective To investigate the effect of fasudil for the patients of anophosphorus pesticide(AOPP) on
the incidence rate anophosphate induced delayed neuropathy. Methods 80 severe patients of AOPP were randomly di-
vided into two groups(n=40):control group and fasudil group. The two groups were given bined therapy of atropine, pene-
hyclidine -pyridine aldoxime methyl chloride, clinical manifestations were measured, the incidence of OPIDN
was estimated. clinical manifestations and indexes of neuro-electrophysiology were measured, clinical therapeutic effect was
estimated. Results In this experiment conditio