影响猪卵母细胞体外成熟的相关因素-生物通.doc

中国农业科学 2006,39(9):1891-1896
Scientia Agricultura Sinica
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影响猪卵母细胞体外成熟的相关因素
张莉,冯书堂
(中国农业科学院北京畜牧兽医研究所,基因与细胞工程研究室,北京 100094)
摘要:卵母细胞是胚胎工程和发育生物学的重要组成部分,它是体外受精、性别控制、克隆及转基因等技术成功与否的前提和关键。影响猪卵母细胞体外成熟的因素很多,本文将从物理因素和化学因素两方面作简要综述。
关键词:猪;卵母细胞;体外成熟;物理因素;化学因素
Factors with in vitro Maturation of Porcine Oocytes
ZHANG Li,FENG Shu-tang
(Department of Gene and Animal Cell Engineering, Institute of Animal Science,
Chinese Academy of Agricultural Sciences, Beijing 100094)
Abstract: Oocyte in vitro maturation plays an important role in embryonic engineering such as in vitro fertilization, nuclear transfer, sex control, cloning and gene transfer. The in vitro maturation of porcine oocytes is the crucial step and precondition in embryo production. It is affected by various factors. In this study, physical and chemical factors in vitro maturation of porcine oocytes are discussed.
Key words: Porcine; Oocyte; in vitro maturation; Physical factors; Chemical factors
收稿日期:2005-02-04;接受日期:2006-03-31
基金项目:国家“863”计划项目(2003AA205103)资助
作者简介:张莉(1975-),女,新疆奇台人,硕士,研究方向为胚胎工程。Tel: 010-62815893; E-mail: zhangli712@。通讯作者冯书堂(1945-),男,河北大名人,研究员,研究方向为动物繁殖胚胎工程。Tel: 010-62815893; E-mail: fst508@
中国农业科学 2006,39(9):1891-1896
Scientia Agricultura Sinica
猪胚胎工程已极大地推进了畜牧业和医学的进程,通过它可以改良品种、培育抗病猪种、提高肉质、生产转基因猪或基因组修饰猪、制备人类疾病模型、进行器官移植、生产药物蛋白、研究发育机理