HCG 日血清激素水平对供精体外受精妊娠结局的影响.doc

HCG日血清激素水平对供精体外受精妊娠结局的影响
刘芳,李丽,王兴玲*,王婧彦,,冯涵琪
郑州大学第三附属医院生殖医学中心(河南郑州) 450052
【摘要】目的:探讨在控制性超排卵(COH)过程中人绒毛膜促性腺激素(human chorionic gonadotropin HCG)注射日激素水平与供精体外受精-胚胎移植(in vitro fertilization and embryo transfer with donor seman,IVF-D /ICSI-D)结局的关系。方法:回顾性分析2007年12月至2011年10月在我中心行IVF-D或ICSI-D助孕的157例患者170个取卵周期资料,比较妊娠组及非妊娠组HCG日激素水平与妊娠结局的相关性,并根据HCG日孕***(P)水平分为P≤>,比较两组间的各项指标变化。结果:妊娠组HCG日孕***水平明显低于未妊娠组,差异有统计学意义(p<);P>≤、获卵率升高(p<),而可利用胚胎率、优质胚胎率降低(p<),胚胎种植率和临床妊娠率明显降低,差异有统计学意义(p<);两组受精率、卵裂率及冻融胚胎移植周期临床妊娠率差异无统计学意义(p>)。结论:HCG日孕***水平一定程度上影响卵子质量及子宫内膜容受性,根据HCG日P值可有效预测供精体外受精胚胎移植的妊娠结局。
【关键词】:HCG,孕***水平,供精体外受精-胚胎移植,妊娠结局
中国图书分类号文献标识码文章编号
Impact of progesterone level on the day of Human chorionic gonadotropin administration on e of in vitro fertilization with donor seman
Liu Fang, Lili,Wang Xingling,Wang Jingyan,Feng Hanqi
Reproductive Center of the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,Henan, China
【Abstract】Objective:To discuss the impact of hormone level on the day of human chorionic gonadotropin administration on pregnancy e of in vitro fertilization and embryo transfer with donor seman in controlled ovarian hyperstimulation. Methods: Retrospective analysis the information of 157 patients of 170 fresh cycles ,who had received IVF-D/ICSI-D in our reproductive medical centre from December 2007 to October 20