分子诊断学 复杂性疾病的分子诊断资料.ppt

分子诊断学_复杂性疾病的分子诊断资料:urrence,usuallywithoutgraveconsequences,:ordingtonumerousinformationavailable,roups:chromosomaldisorders,monogenicorsingle-genedisorders,:染色体;monogenic/single-gene:单基因;polygenic/icand/icfactorsthatdonotconformtotraditionalMendelianinheritancepattens,:后生的;Mendelianinheritance:孟德尔遗传;:***化;pathogenic:病原的Hybridization::血浆或血清potentially:潜在地DNAalterationshavebeendetectedinpatientswithsmalloreveninsitulesions,:改变,更改;insitu:在原来的位置;lesion:机能障碍;Oureverbroadeninginsightsintothemolecularbasisofdiseaseprocessescontinuetoprovideanopportunityfortheclinicallaboratorytodevelopandimplementnewandnovelapproachesfordiagnosis,monitoring,:实施;prognostic:预兆复杂性疾病包括肿瘤(tumor)、心血管疾病(cardiovasculardiseases)、自身免疫性疾病(autoimmunediseases)和一些代谢性疾病(metabolicdiseases)等。