(1)April25,1953(2),Nature(3),171,737-738Wewishtosuggestastructureforthesaltofdeoxyribosenucleicacid(.).(4),withthephosphatesnearthefibreaxis,,thisstructureisunsatisfactoryfortworeasons:(1)WebelievethatthematerialwhichgivestheX-raydiagramsisthesalt,,especiallyasthenegativelychargedphosphatesneartheaxiswillrepeleachother.(2)-chainstructurehasalsobeensuggestedbyFraser(inthepress).Inhismodelthephosphatesareontheoutsideandthebasesontheinside,-defined,(5).Thisstructurehastwohelicalchainseachcoiledroundthesameaxis(seediagram).Wehavemadetheusualchemicalassumptions,namely,thateachchainconsistsofphosphatediestergroupsjoiningbeta-D-deoxyribofuranoseresidueswith3',5'(butnottheirbases)-handedhelices,b
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