cerebrospinal fluid examination-山东大学邮件系统-.ppt

CEREBROSPINAL FLUID EXAMINATION
Institute of Diagnostics
Zhong Ning
Email: ******@sdu.
CONTENT
Preface
Specimen Collection
Opening Pressure
Total cell count
Differential cell count
Glucose
Protein
2005-5-17
Medicine School of Shandong University
Preface
Cerebrospinal fluid (CSF) is mostly derived through the choroid plexuses.
500mL/day approximately
CSF protects the brain and spinal cord, and collects waste, circulates nutrients, cushions and lubricates the central nervous system (CNS).
2005-5-17
Medicine School of Shandong University
2005-5-17
Medicine School of Shandong University
The blood-brain barrier
BBB is a concept derived from dye-exclusion studies rather than a specific anatomic structure.
Certain substances in the CSF are tightly regulated by specific transport systems.
2005-5-17
Medicine School of Shandong University
2005-5-17
Medicine School of Shandong University
Specimen Collection
Lumbar puncture (LP) is the insertion of a needle into the subarachnoid space (the area under the membrane that surrounds the brain and spinal cord) of the lumbar (lower back) region for diagnostic or therapeutic purposes. This allows access to the cerebrospinal fluid (CSF) in which the brain and spinal cord float.
Although the subarachnoid space can be accessed from other levels, the lumbar region is most often used as it allows the needle to be inserted below the end of the spinal cord.
2005-5-17
Medicine School of Shandong University
2005-5-17
Medicine School of Shandong University