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阿尔兹海默症诊断新标准.doc

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阿尔兹海默症诊断新标准.doc:..NEWCRITERIAANDGUIDEUNESFORTHEDIAGNOSISOFALZHEIMEFVSDISEASEPUBLISHEDFORFlRSTTIMEIN27YEARS・ResearchAgendaSuggestedforDetectingPre-SymptomaticAlzheimer's―NewAlzheimer'sDefinitionMovesResearchersClosertoEarlyDetectionandIntervention-CHICAGO,April19,2011一Forthefirsttimein27years,newcriteriaandguidelinesforthediagnosisofAlzheimer'sdiseasehavebeenpublishedbythreeexpertworkgroupsspearheadedbytheAlzheimer'sAssociationandtheNationalInstituteonAging(NIA)oftheNationalInstitutesofHealth(NIH).Theworkgroupspublishedfourarticlesincludingready-to-riteriaforAlzheimer'sdiseasedementiaandmildcognitiveimpairment(MCI)duetoAlzheimer'''sdementiaandMCIduetoAlzheimer'swasalsoproposedasaresearchagendaonl%,theNationalInstituteonAging/Alzheimer'sAssociationDiagnoSticGuidelinesforAlzheimer'sDisease一expandthedefinitionofAlzheimer'stoineludetwonewphasesofthedisease:(1)presymptomaticand(2)mildlysymptomaticbutpre-dementia,alongwith(3)dementiacausedbyAlzheimer''andmeasurablechangesinthebrainsofaffectedpeopleyears,perhapsdecades,,bringthefieldclosertoearlierdetect!onandtreatment,andultimatelyleadtoeffectivedisease-modifyingtherapies/saidWilliamThies,.,ChiefMedicalandScientificOfficerattheAlzheimer',riteriaforAlzheimer's,butisanothermajorstepintheprocess/''Thenewguidelinesreflecttoday'sunderstandingofhowkeychangesinthebrainleadtoAlzheimer'sdiseasepathologyandhowtheyrelatetotheclinicalsignsofmildcognitiveimpairmentandAlzheimer'sdiseasedementia/saidCreightonPhelps,.,ProgramDirector

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