瑞波西汀与氯丙咪嗪治疗抑郁症伴焦虑临床评价.doc

瑞波西汀与***内咪嗪治疗抑郁症伴焦虑临床评价作者:左桂连,林怀洁单位:1•广东省汕头市第四人民医院,,广东汕头515000【摘要】目的:比较瑞波西汀与***丙咪嗪治疗抑郁症伴焦虑的疗效及英安全性。方法:将111例抑郁症分为两组。瑞波西汀组56例,口服瑞波西汀8〜12mg,2次/日;***,口服***内咪嗪100〜200mg,2次/日;均6周为1个疗程。结果:对抑郁症状的治疗,%,***%,疗效差异无显著意义(P>);对焦虑症状的治疗,瑞波西汀纽•%0***%,疗效差异有显著性(P<),整体药物不良反应发生率两组相当。结论:瑞波西汀与***丙咪嗪是安全有效的治疗抑郁症的药物,但抗焦虑作用瑞波西汀优于***丙咪嗪。【关键词】瑞波西汀***丙咪嗪抑郁症焦虑ClinicalEvaluationonReboxetineandClomipramineintheTreatmentofDepressiveDisorderAssociatedwithAnxietyZUOGui-lian,etalTheForthPeople&rsquo;sHospitalofShantou,GuangdongShantou515000,ChinaAbstract:Objective::OnehundredandelevenPatientsdepressionassociatedwithanxietyweredividedinto2groups:Fifty-sixPatientsweretreatedwithreboxetine,8〜12mg,po,bidfor6weeks;fifty-fivepatientsweretreatedwithclomipramine,100〜200ing,po,:%%(p>)intreatingdepressionsymptoms,%%(p<):Reboxetineandclomipramineisasafeandeffectivechugfortreatmentofdepression,butreboxetineissuperiortoclomipramineinreducinganxietysy