4-苯氧基苯酚的合成改进20386.pdf.pdf

化学世界 。陶建伟。陆庆宁。金东元(上海应用技术学院化工系,上海200235) 2007年摘要:以二苯醚和苯甲酰氯为原料,,然后再经Beayer-。主要考察Beayer-villyger氧化反应中反应温度、反应时间、原料配比等因素对产物收率的影响。结果表明,在40。C、7h、n(过氧化氢):n(硫酸):n()=::,Beayer—%。在上述条件下,经三步反应,,其总收率达80%以上。经熔点、红外光谱及元素分析确定产物为4. 苯氧基苯酚。关键词:;合成;二苯醚;苯甲酰氯;;: 文献标识码:A 文章编号:(2007) ImprovementonSynthesisof4一Phenoxyphenol GAOYong—hong,TAOJian—wei,LUQing—ning,JINDong-yuan (DepartmentofChemicalEngtneering,ShanghaiInstituteofTechnology,Shanghai200235,China) Abstract:4-Phenoxyphenolwassynthesizedfrom4-phenoxy·-diphenylketonepreparedwithdiphenyletherandbenzoyl chlorideaslawmaterialthroughBeayer—,reactiontime andtemperatureonBeayer-:rt(H202):rt (H2SO4):n(4-phenoxy—diphenylketone)=::;reactiontime,7h,temperature,40。- %andtheoverallyieldof4-phenoxyphenolwasabout80%.Theproductswerecharacterized byIR,elementalanalysisandmeltingpointtest. Keywords:4-phenoxyphenyl;synthesis;diphenylether;benzoylchloride;4-phenoxy—diphenylketone;Beayer-villyger oxidetion 、保幼醚、蚊绳醚等农药的重要中间体,:对苯二酚法、对氯苯酚法。’、对苯氧基苯胺和二苯醚法”。对苯二酚法由于原料对苯二酚易氧化,副产物多,收率较低;对氯苯酚法反应温度较高,反应条件不易控制;对苯氧基苯胺法因原料价格较贵,工业化的经