AnemiaintheICU:AnEvidenceBasedApproachOverviewWhatiscurrenttransfusionpractice?Whataretherisksoftransfusion?Isthereanoptimalhemoglobin?AretherealternativestotheuseofpRBCs??AnyindicationCostsofTransfusionSomeestimatesrangefrom$100-$150/ountforCostsofnursingtimeCostsofadditionaltestingCostsofreactionsMorerecentestimates:$250-$300/antor,;16:(NAT)Estimatedincreaseincostovernextseveralyears:$50-$100/unitNewtotalcosttohealthcaresystem-->atleast$60millionTransfusionintheICURetrospectivereviewofpatientsinICU>1week85%receivedpRBCsAveragetransfusion:: 29%LowHct: 19%Averagedailybloodlossfromphlebotomy:70ml/dayCorwin,;108:%MMDparticipatedQueriedregardingCurrenttransfusionpracticeinICUPresentedwithhypotheticalcasesHebert,;26:-academicMDs(p<)Onceathresholdwasreached,>90%ofMDstransfused2unitsTransfusionintheICUOnaverage,pRBCsusedintheICUAreatleast2weeksoldLacksufficient2,3DPGHavediminishedO2carryingcapacityRemaininthecirculationforonlyashorttimeRisksofTransfusionInfectionTransfusionreactionImmunomodulatoryVolume-related
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